From St Louis, MO (Lambert International Airport - STL)
Approximately 80 miles 1 hr 30 min
- Start out going NORTHWEST on LAMBERT INTERNATIONAL BLVD toward NATURAL BRIDGE RD.
- Turn RIGHT onto LAMBERT INTERNATIONAL BLVD/NATURAL BRIDGE RD.
- Merge onto I-70 W via the ramp on the LEFT.
- Merge onto US-61 N via EXIT 210B toward HANNIBAL.
- Take the MO-161 ramp toward BOWLING GREEN/ASHLEY.
- Turn LEFT onto Business US-61 BR/MO-161.
- Turn RIGHT on W MAIN ST.
- Turn LEFT on N MAIN CROSS ST.
- Turn LEFT on SOLUTION PLACE.

From Columbia,MO (Columbia Regional Airport - COU)
Approximately 145 miles 2 hrs 30 min
- Start out going NORTHWEST on S AIRPORT RD toward MO-H.
- Turn LEFT onto MO-H.
- Turn RIGHT onto US-63 N.
- Take the ramp toward I-70/ US-40/ ST LOUIS/ MO-PP/ KANSAS CITY.
- Merge onto N US-63.
- Merge onto I-70 E/ US-40 E toward ST LOUIS.
- Merge onto US-61 N via EXIT 210 toward HANNIBAL.
- Take the MO-161 ramp toward BOWLING GREEN/ASHLEY.
- Turn LEFT onto Business US-61 BR/MO-161.
- Turn RIGHT on W MAIN ST.
- Turn LEFT on N MAIN CROSS ST.
- Turn LEFT on SOLUTION PLACE.

From Quincy, IL (Quincy Regional Airport - UIN)
Approximately 65 miles 1 hr 20 min
- Start out going SOUTH on E 1700TH ST toward N 1200TH AVE/IL-104 W.
- Turn RIGHT onto HWY 104/N 1200TH AVE/IL-104 W. Continue to follow IL-104 W.
- Merge onto I-172 S via the ramp on the LEFT.
- Merge onto I-72 W/US-36 W via EXIT 0 toward HANNIBAL (Crossing into MISSOURI).
- Take the US-61 exit toward NEW LONDON/PALMYRA.
- Turn SLIGHT LEFT onto US-36 BR/US-61/MCMASTERS AVE. Continue to follow US-61 S.
- Merge onto US-61 N via EXIT 210 toward HANNIBAL.
- Take the MO-161 ramp toward BOWLING GREEN/ASHLEY.
- Turn RIGHT onto Business US-61 BR/MO-161.
- Turn RIGHT on W MAIN ST.
- Turn LEFT on N MAIN CROSS ST.
- Turn LEFT on SOLUTION PLACE.